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Hip Dysplasia: A developmental orthopedic disease causing abnormal hip joint formation, leading to osteoarthritis

The mechanism involves stimulating over 300 different genes associated with tissue repair and remodeling, fibroblast activation and collagen synthesis, epidermal basal stem cell viability, an anti-inflammatory effect, an antioxidant effect and stimulation of microvascular growth

Moreover, the dose-dependent effect of HLA-DR2 haplotypes on MS susceptibility suggests a potential link between genetic factors and disease manifestation [153]

POLK overexpression contributes to cancer development by inactivating wild-type p53, and this was shown in lung cancer 47